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08/09/2017 - 10:57am

Old animals injected with the hormone component klotho learn and remember better

08/09/2017 - 10:26am

It is not always good to have the opportunity to make a choice. When we must decide to take one action rather than another, we also, ordinarily, become at least partly responsible for what we choose to do. Usually this is appropriate; it’s what makes us the kinds of creatures who can be expected to abide by moral norms

08/09/2017 - 10:13am

by Craig Klugman, Ph.D.

Last week the U.S. Senate passed bill S. 204, the Trickett Wendler Right to Try Act of 2017. Trickett Wendler was a woman with ALS. The ALS association and her family lobbied Congress to support this bill to give all patients living with a terminal illness the “right” to purchase experimental drugs from pharmaceutical companies. Essentially, this bypasses the FDA’s compassionate use program. Instead of filing an application for FDA compassionate use (which the FDA approves 99% of the time), the patient asks the drug manufacturer directly.…

08/09/2017 - 10:04am

Juan Carlos Izpisua Belmonte had spent years probing the inner workings of embryos, ferreting out the genes that give a body its shape or allow wings to form instead of legs. He’d tracked wafting chemical messengers that, like traffic police, guide streams of dividing cells either left or right. He’d even found a way to tweak animals to grow extra limbs

08/09/2017 - 9:22am

crossposted from Rising to the Challenge: The Campaign for Johns Hopkins

 

 

 

How should resources be allocated between HIV treatment for those already infected and finding ways to prevent HIV to avert more illness and death in the long run?

 

This is the sort of thorny question Jeremy Sugarman, MD, MPH, MA – deputy director for medicine of the Johns Hopkins Berman Institute of Bioethics and the Harvey “Bud” M. Meyerhoff Professor of Bioethics and Medicine – tackles in his research.

 

And he credits the Meyerhoff Professorship for not only bringing him to Hopkins, but giving him the freedom to take chances in his research and help those who are most vulnerable.

 

“The professorship made it possible to explore things that were a little bit more risky in bioethics. Classically, we need to raise money to do particular projects, and those particular projects are very circumscribed. We can’t always take on a venture, something new, something unusual,” Sugarman explains.

 

“The professorship gave me the opportunity to work with colleagues in the School of Medicine, in the Bloomberg School of Public Health, and across the university, on questions of bioethics that otherwise may not be addressed,” he says. Some of these earlier projects involved international HIV prevention trials in border regions of China and Thailand and preventing HIV transmission from mother to child in Uganda.

 

“Previously, I wouldn’t have time to just leave, go on a trip, work with those people, and grapple with some of the ethical issues that people around the globe were facing. Those efforts have subsequently led to long‑standing projects,” Sugarman says. More recent research has also involved the ethics of organ transplants from HIV-positive donors. (Johns Hopkins Medicine performed the world’s first liver transplant from a HIV-positive donor to a HIV-positive patient in 2016.)

 

In addition to what the endowed professorship has allowed in terms of scholarly research, Sugarman says he has also appreciated getting to know Meyerhoff personally.

 

“Bud played a key role in making the Berman Institute what it is today, and I am simpatico with Bud. He demands a lot. I demand a lot. He’s meticulous. I’m meticulous,” says Sugarman, who is also co-chair of the Johns Hopkins Institutional Stem Cell Research Oversight Committee and whose work also addresses the ethics of informed consent, umbilical cord blood banking, and stem cell research.

 

“And I’ve always told Bud that it’s an honor to have his name on my business card for the rest of my life,” he adds.

 

 

To learn how you can make a gift to support the Berman Institute of Bioethics, please contact Andrea Matz.

08/09/2017 - 4:00am

Variability in ICU treatment has been well documented.  In contrast, I had understood that EMS resuscitated and transported everyone who was not obviously dead. 

08/09/2017 - 4:00am

Variability in ICU treatment has been well documented.  In contrast, I had understood that EMS resuscitated and transported everyone who was not obviously dead. 

But apparently there is variability even there. A new article in Resuscitation ...

08/08/2017 - 12:34pm

Immortality has gone secular. Unhooked from the realm of gods and angels, it’s now the subject of serious investment – both intellectual and financial – by philosophers, scientists and the Silicon Valley set. Several hundred people have already chosen to be ‘cryopreserved’ in preference to simply dying, as they wait for science to catch up and give them a second shot at life

08/08/2017 - 12:30pm

“A crippling problem.” “A total epidemic.” “A problem like nobody understands.” These are the words President Trump used to describe the opioid epidemic ravaging the country during a White House listening session in March